o ok, well i was just confused about it, cus you know this is a game forum, and he is talking about fighting aging? but i guess it makes sence.
, sorry about that mzoltan22, great artical tho
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| Author: | mzoltan22 [ Thu Feb 17, 2011 6:29 am ] |
| Post subject: | fighting aging |
check this out: sens.org . You can also search on youtube about Aubrey de Gray, for some intresting quick informations on the matter. Some words on it: altough it lists 7 causes of aging, it in reality might not be like 7 equal parts to solve. as far as i can tell, the key part to solve is making stem cell therapies efficient to the level, where it could provideopenended youth. tough, for some serious brain conditions, it is quite evident that by using stem cell therapy, a lot of new nervcell replacements would be needed in a short period of time, so there is a great potential, that the new fresser brain would be very differently wired, so the old personality would change drastically (also, there might be some areas, where the wiring of nerve cells is even more crusial). Nerve cells are non dividing cells as far as i know, so their telomers wont shorten with time (altho tthere are some glial cells in the brain, wich give rise to new neurons, hence they divide). If a cell doesn't divide it has a greater risk of accumulating undigestable intercellular junk in its lyposome, making its function less effiient. it is said, that mitocondrial mutation, is quite frequent wich leads to some cells with some mitocondrial genes being delted, causing the mitocondrion to become inoperational. This is hypothesized to be caused by the high reagent oxigen species present in the mitocondrion. apparently, there must be some kind of cells, wich is protected against it, otherwise humanity would die out pretty quickly. so with stem cell research, one important goal, is to brew stem cells cheaply in masses. So at some point the stem cells must have active enzimes to lengthen their telomers, and they must escape mitocondrial mutations. after that, people have to learn how to turn them into different cells. so there are a lot of things to do. with stem cells, most of the cells of the body could be replaced with completly fresh ones. for examle, they could make it so, that they make cells suicide (there are sucide signals; most of them are used to kill exess amount of dividing cells; or in development, to develop fingers for example); then they inject stemcells, wich will some way get turned into tissue. now here, there is two obvious thing also needed: endocitosis of junk left behind by dead cells, digestion, or disposition of such junk. But for the brain, it is a must to get intracellular junk out of the lyposomes and dispose of it, or do it as they describe (gene manipulation so, a new gene would be added, wich would create enzime, wich would digest undigestable). But i guess the disposition method might be actually better(since the junk might be to hard to digest, but if there is some tough enzime, you have to activate it only if you find junk, or otherwise, it could do harm to the soft things too; or they could be compatible with other substrates[wich is no problem if those are outside of the lyposome]). So its complicated stuff, although they list quite good ideas. P S Even if they are lying about some progress, i think it would be good to concentrate on it more, cince certain death is at some points a pressure on some people, and pressure make unhappiness. Also, open ended youth would eliminate the huge time and effort required to train next generations of humans. |
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| Author: | Sarge [ Mon Mar 14, 2011 11:30 pm ] |
| Post subject: | Re: fighting aging |
are you high? lol kinda an odd place foe this dont you think? |
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| Author: | mzoltan22 [ Tue Mar 15, 2011 1:49 am ] |
| Post subject: | Re: fighting aging |
Sarge wrote: are you high? lol kinda an odd place foe this dont you think? well, its in "chit-chat". if someone is intrested will check it out. thats about it. |
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| Author: | Sarge [ Tue Mar 15, 2011 3:06 pm ] |
| Post subject: | Re: fighting aging |
o ok, well i was just confused about it, cus you know this is a game forum, and he is talking about fighting aging? but i guess it makes sence. , sorry about that mzoltan22, great artical tho
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| Author: | mzoltan22 [ Thu Mar 17, 2011 9:08 am ] |
| Post subject: | Re: fighting aging |
No harm done. |
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